Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family.

Saito, Akihiko; F. Pietromonaco, Salvatore; K Loo, A; G Farquhar, M

doi:10.1073/pnas.91.21.9725

Public

Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family.

Published in Proceedings of the National Academy of Sciences • Oct 11, 1994

Authors:

Akihiko Saito

Salvatore F. Pietromonaco

A K Loo

Abstract

We completed the cDNA cloning and sequencing of gp330, the major kidney glomerular antigen for rat Heymann nephritis. The deduced 4660-aa sequence, expected to constitute a mature protein of M(r) 516,715, consists of a probable N-terminal signal peptide sequence (25 aa), an extracellular region (440...

Subject

LDL receptor

Biology

Peptide sequence

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