Subcutaneous administration of botulinum toxin A reduces formalin-induced pain

Cui, Minglei; Khanijou, Sid; Rubino, John; Roger Aoki, K.

doi:10.1016/j.pain.2003.10.008

Public

Subcutaneous administration of botulinum toxin A reduces formalin-induced pain

Published in Pain • Dec 9, 2003

Authors:

Minglei Cui

Sid Khanijou

John Rubino

Abstract

Botulinum toxin type A (BoNT-A) produced by the bacterium Clostridium botulinum is a potent inhibitor of acetylcholine release in the neuromuscular junction and has been used to treat many disorders related to excessive muscle contraction. However, BoNT-A has recently been used in pain therapy to tr...

Subject

Nociception

Medicine

Botulinum toxin

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