Multitarget Therapy for Induction Treatment of Lupus Nephritis

Liu, Zhihong; Zhang, Haitao; Liu, Zhangsuo; Changying, Xing; Fu, Ping; Ni, Zhaohui; Chen, Jianghua; Lin, Hongli; Liu, Fuyou; He, Yongcheng; He, Yani; Miao, Lining; Chen, Nan; Li, Ying; Gu, Yong; Shi, Wei; Hu, Weixin; Liu, Zhengzhao; Bao, Hao; Zeng, Caihong; Zhou, Minlin

doi:10.7326/m14-1030

Public

Multitarget Therapy for Induction Treatment of Lupus Nephritis

Published in Annals of Internal Medicine • Nov 10, 2014

Authors:

Zhihong Liu

Haitao Zhang

Zhangsuo Liu

Abstract

BACKGROUND: Treatment of lupus nephritis (LN) remains challenging. OBJECTIVE: To assess the efficacy and safety of a multitarget therapy consisting of tacrolimus, mycophenolate mofetil, and steroid compared with intravenous cyclophosphamide and steroid as induction therapy for LN. DESIGN: 24-week ra...

Subject

Medicine

Lupus nephritis

Cyclophosphamide

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