Biochemistry and Molecular Biology of Gelatinase B or Matrix Metalloproteinase-9 (MMP-9)

E. Van den Steen, Philippe; Dubois, Bénédicte; Nelissen, Inge; M. Rudd, Pauline; A. Dwek, Raymond; Opdenakker, Ghislain

doi:10.1080/10409230290771546

Public

Biochemistry and Molecular Biology of Gelatinase B or Matrix Metalloproteinase-9 (MMP-9)

Published in Critical Reviews in Biochemistry and Molecular Biology • Jan 1, 2002

Authors:

Philippe E. Van den Steen

Bénédicte Dubois

Inge Nelissen

Abstract

The matrix metalloproteinases (MMPs) form an enzyme family of which gelatinase B (MMP-9) represents the largest and most complex member. We focus here on the biochemical properties, regulation, and functions of gelatinase B. The tight regulation of gelatinase B activity is highly complex and is esta...

Subject

Gelatinase A

Matrix metalloproteinase

Gelatinase

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