Quantitative and stoichiometric analysis of the microRNA content of exosomes

R. Chevillet, John; Kang, Qing; K. Ruf, Ingrid; Briggs, Hilary; Vojtech, Lucia; M. Hughes, Sean; H. Cheng, Heather; D. Arroyo, Jason; Meredith, Emily; N. Gallichotte, Emily; L. Pogosova‐Agadjanyan, Era; Morrissey, Colm; L. Stirewalt, Derek; Hladik, Florian; Y. Yu, Evan; S. Higano, Celestia; Tewari, Muneesh

doi:10.1073/pnas.1408301111

Public

Quantitative and stoichiometric analysis of the microRNA content of exosomes

Published in Proceedings of the National Academy of Sciences • Sep 29, 2014

Authors:

John R. Chevillet

Qing Kang

Ingrid K. Ruf

Abstract

Exosomes have been proposed as vehicles for microRNA (miRNA) -based intercellular communication and a source of miRNA biomarkers in bodily fluids. Although exosome preparations contain miRNAs, a quantitative analysis of their abundance and stoichiometry is lacking. In the course of studying cancer-a...

Subject

Microvesicles

Exosome

microRNA

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