Fluorouracil vs Gemcitabine Chemotherapy Before and After Fluorouracil-Based Chemoradiation Following Resection of Pancreatic Adenocarcinoma

F. Regine, William; Winter, Kathryn; A. Abrams, Ross; Safran, Howard; P. Hoffman, John; Konski, André; B. Benson, Al; S. Macdonald, John; Kudrimoti, Mahesh; Fromm, Mitchel; G. Haddock, Michael; Schaefer, Paul; G. Willett, Christopher; A. Rich, Tyvin

doi:10.1001/jama.299.9.1019

Public

Fluorouracil vs Gemcitabine Chemotherapy Before and After Fluorouracil-Based Chemoradiation Following Resection of Pancreatic Adenocarcinoma

Published in JAMA • Mar 4, 2008

Authors:

William F. Regine

Kathryn Winter

Ross A. Abrams

Abstract

CONTEXT: Among patients with locally advanced metastatic pancreatic adenocarcinoma, gemcitabine has been shown to improve outcomes compared with fluorouracil. OBJECTIVE: To determine if the addition of gemcitabine to adjuvant fluorouracil chemoradiation (chemotherapy plus radiation) improves surviva...

Subject

Medicine

Gemcitabine

Fluorouracil

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