TLR2 engagement on CD8 T cells lowers the thresholdfor optimal antigen‐induced T cell activation

Cottalorda, Anne; Verschelde, Claire; Marçais, Antoine; Tomkowiak, Martine; Musette, Philippe; Uematsu, Satoshi; Akira, Shizuo; Marvel, Jacqueline; Bonnefoy, Nathalie

doi:10.1002/eji.200636181

Public

TLR2 engagement on CD8 T cells lowers the thresholdfor optimal antigen‐induced T cell activation

Published in European Journal of Immunology • Jun 8, 2006

Authors:

Anne Cottalorda

Claire Verschelde

Antoine Marçais

Abstract

TLR have a crucial role in the detection of microbial infection in mammals. Until recently, most investigations on TLR have focused on cells of the innate immune system and on the role of TLR in the initiation of antigen-specific responses following recognition of microbial products by APC. Here, we...

Subject

Cytotoxic T cell

Biology

IL-2 receptor

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