Mice with Low Metabolic Rates Are Not Susceptible to Weight Gain When Fed a High‐Fat Diet

Hambly, Catherine; C. Adams, Andrew; Fustin, Jean‐Michel; A. Rance, K.; Bünger, L.; R. Speakman, John

doi:10.1038/oby.2005.59

Public

Mice with Low Metabolic Rates Are Not Susceptible to Weight Gain When Fed a High‐Fat Diet

Published in Obesity Research • Mar 1, 2005

Authors:

Catherine Hambly

Andrew C. Adams

Jean‐Michel Fustin

Abstract

OBJECTIVE: Mice divergently selected for high or low food intake (FI) at constant body mass differ in their resting metabolic rates (RMRs). Low-intake individuals (ML) have significantly lower RMR (by 30%) compared with those from the high-intake line (MH). We hypothesized that MLs might, therefore,...

Subject

Calorie

Internal medicine

Endocrinology

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