Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

Thorens, Bernard

doi:10.1073/pnas.89.18.8641

Public

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

Published in Proceedings of the National Academy of Sciences • Sep 15, 1992

Authors:

Bernard Thorens

Abstract

Glucagon-like peptide 1 (GLP-1) is a hormone derived from the preproglucagon molecule and is secreted by intestinal L cells. It is the most potent stimulator of glucose-induced insulin secretion and also suppresses in vivo acid secretion by gastric glands. A cDNA for the GLP-1 receptor was isolated ...

Subject

Secretin family

Secretin

Glucagon-like peptide 1 receptor

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