ESI‐MS/MS analysis of underivatised amino acids: a new tool for the diagnosis of inherited disorders of amino acid metabolism. Fragmentation study of 79 molecules of biological interest in positive and negative ionisation mode

Piraud, Monique; Vianey‐Saban, Christine; Pétritis, Konstantinos; Elfakir, Claire; Steghens, Jean‐Paul; Morla, A.; Bouchu, Denis

doi:10.1002/rcm.1054

Public

ESI‐MS/MS analysis of underivatised amino acids: a new tool for the diagnosis of inherited disorders of amino acid metabolism. Fragmentation study of 79 molecules of biological interest in positive and negative ionisation mode

Published in Rapid Communications in Mass Spectrometry • May 14, 2003

Authors:

Monique Piraud

Christine Vianey‐Saban

Konstantinos Pétritis

Abstract

The diagnosis of inherited disorders of amino acids (AA) metabolism is usually performed on automated analysers by ion-exchange chromatography and quantification after ninhydrin derivatisation of about 50 different AA. A single run liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for...

Subject

Chemistry

Mass spectrometry

Chromatography

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!