MicroRNA‐140 is expressed in differentiated human articular chondrocytes and modulates interleukin‐1 responses

Miyaki, Shigeru; Nakasa, Tomoyuki; Otsuki, Shuhei; P. Grogan, Shawn; Higashiyama, Reiji; Inoue, Atsushi; Kato, Yoshio; Sato, Tempei; Lotz, Martin; Asahara, Hiroshi

doi:10.1002/art.24745

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MicroRNA‐140 is expressed in differentiated human articular chondrocytes and modulates interleukin‐1 responses

Published in Arthritis & Rheumatism • Aug 27, 2009

Authors:

Shigeru Miyaki

Tomoyuki Nakasa

Shuhei Otsuki

Abstract

OBJECTIVE: MicroRNA (miRNA) are a class of noncoding small RNAs that act as negative regulators of gene expression. MiRNA exhibit tissue-specific expression patterns, and changes in their expression may contribute to pathogenesis. The objectives of this study were to identify miRNA expressed in arti...

Subject

microRNA

Chondrogenesis

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