hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer

Camps, Carme; M. Buffa, Francesca; Colella, Stefano; Moore, John; Sotiriou, Christos; Sheldon, Helen; L. Harris, Adrian; Gleadle, Jonathan; Ragoussis, Jiannis

doi:10.1158/1078-0432.ccr-07-1755

Public

hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer

Published in Clinical Cancer Research • Mar 1, 2008

Authors:

Carme Camps

Francesca M. Buffa

Stefano Colella

Abstract

PURPOSE: MicroRNA (miRNA) expression alterations have been described in cancer. Many cancers are characterized by areas of hypoxia, enhanced hypoxia-inducible factor (HIF) levels, and increased expression of hypoxically regulated genes, all of which correlate with patient outcome. We examined hypoxi...

Subject

Breast cancer

microRNA

Hypoxia (environmental)

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