Peginterferon Alfa-2b or Alfa-2a with Ribavirin for Treatment of Hepatitis C Infection

G. McHutchison, John; Lawitz, Eric; L. Shiffman, Mitchell; J. Muir, Andrew; Galler, Greg; McCone, Jonathan; M. Nyberg, Lisa; M. Lee, William; Ghalib, Reem; R. Schiff, Eugene; Galati, Joseph; R. Bacon, Bruce; Davis, Mitchell; Mukhopadhyay, Pabak; Koury, Kenneth; Noviello, Stephanie; D. Pedicone, Lisa; A. Brass, Clifford; K. Albrecht, Janice; Sulkowski, Mark

doi:10.1056/nejmoa0808010

Public

Peginterferon Alfa-2b or Alfa-2a with Ribavirin for Treatment of Hepatitis C Infection

Published in New England Journal of Medicine • Jul 23, 2009

Authors:

John G. McHutchison

Eric Lawitz

Mitchell L. Shiffman

Abstract

BACKGROUND: Treatment guidelines recommend the use of peginterferon alfa-2b or peginterferon alfa-2a in combination with ribavirin for chronic hepatitis C virus (HCV) infection. However, these regimens have not been adequately compared. METHODS: At 118 sites, patients who had HCV genotype 1 infectio...

Subject

Medicine

Ribavirin

Peginterferon alfa-2a

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