A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia

A. Calin, George; Ferracin, Manuela; Cimmino, Amelia; Di Leva, Gianpiero; Shimizu, Masayoshi; E. Wojcik, Sylwia; V. Iorio, Marilena; Visone, Rosa; İlter Sever, Nurettin; Fabbri, Muller; Iuliano, Rodolfo; Palumbo, Tiziana; Pichiorri, Flavia; Roldo, Claudia; Garzon, Ramiro; Sevignani, Cinzia; Z. Rassenti, Laura; Alder, Hansjüerg; Volinia, Stefano; Liu, Chang‐Gong; J. Kipps, Thomas; Negrini, Massimo; M. Croce, Carlo

doi:10.1056/nejmoa050995

Public

A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia

Published in New England Journal of Medicine • Oct 26, 2005

Authors:

George A. Calin

Manuela Ferracin

Amelia Cimmino

Abstract

BACKGROUND: MicroRNA expression profiles can be used to distinguish normal B cells from malignant B cells in patients with chronic lymphocytic leukemia (CLL). We investigated whether microRNA profiles are associated with known prognostic factors in CLL. METHODS: We evaluated the microRNA expression ...

Subject

Chronic lymphocytic leukemia

microRNA

Medicine

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