A Trial of a 9-Valent Pneumococcal Conjugate Vaccine in Children with and Those without HIV Infection

P. Klugman, Keith; A. Madhi, Shabir; Huebner, Robin; Kohberger, Robert; Mbelle, Nontombi; Pierce, Nathaniel

doi:10.1056/nejmoa035060

Public

A Trial of a 9-Valent Pneumococcal Conjugate Vaccine in Children with and Those without HIV Infection

Published in New England Journal of Medicine • Oct 1, 2003

Authors:

Keith P. Klugman

Shabir A. Madhi

Robin Huebner

Abstract

BACKGROUND: Acute respiratory tract infections caused by Streptococcus pneumoniae are a leading cause of morbidity and mortality in young children. We evaluated the efficacy of a 9-valent pneumococcal conjugate vaccine in a randomized, double-blind study in Soweto, South Africa. METHODS: At 6, 10, a...

Subject

Medicine

Pneumococcal conjugate vaccine

Confidence interval

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