A Randomized Trial of Adjuvant Chemotherapy with Uracil–Tegafur for Adenocarcinoma of the Lung

Kato, Harubumi; Ichinose, Yukito; Ohta, Morio; Hata, Enjô; Tsubota, Noriaki; Tada, Hirohito; Watanabe, Yoh; Wada, Hiromi; Tsuboi, Masahiro; Hamajima, Nobuyuki; Ohta, Mitsuo

doi:10.1056/nejmoa032792

Public

A Randomized Trial of Adjuvant Chemotherapy with Uracil–Tegafur for Adenocarcinoma of the Lung

Published in New England Journal of Medicine • Apr 21, 2004

Authors:

Harubumi Kato

Yukito Ichinose

Morio Ohta

Abstract

BACKGROUND: In a previous phase 3 trial of adjuvant chemotherapy after resection of non-small-cell lung cancer, a combination of uracil and tegafur (often referred to as UFT) taken orally was shown to prolong survival. A subgroup analysis disclosed that most patients who benefited had pathological s...

Subject

Tegafur

Medicine

Adenocarcinoma

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