Oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough pain in cancer patients: a controlled dose titration study.

RK, Portenoy; R, Payne; P, Coluzzi; JW, Raschko; A, Lyss; MA, Busch; V, Frigerio; J, Ingham; DB, Loseth; E, Nordbrock; M, Rhiner

doi:10.1016/s0304-3959(98)00179-1

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Oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough pain in cancer patients: a controlled dose titration study.

Shared by NobleBlocks on Feb 1, 1999 • 12:00 AM UTC

Authors:

Portenoy RK

Payne R

Coluzzi P

Abstract

Oral transmucosal fentanyl citrate (OTFC) is a novel opioid formulation in which the potent synthetic mu-agonist fentanyl is embedded in a sweetened matrix that is dissolved in the mouth. It is undergoing investigation as a treatment for cancer-related breakthrough pain, a prevalent phenomenon defin...

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