Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes

Maneiro, Emilia; Á. Martín, Miguel; C. de Andrés, María; López-Armada, M.J.; Fernández-Sueiro, J.L.; del Hoyo, Pilar; Galdo, F.; Arenas, Joaquı́n; J. Blanco, Francisco

doi:10.1002/art.10837

Public

Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes

Published in Arthritis & Rheumatism • Feb 28, 2003

Authors:

Emilia Maneiro

Miguel Á. Martín

María C. de Andrés

Abstract

OBJECTIVE: Osteoarthritis (OA) is a degenerative rheumatic disease that is associated with extracellular matrix degradation and chondrocyte apoptosis in the articular cartilage. The role of mitochondria in degenerative diseases is widely recognized. We undertook this study to evaluate mitochondrial ...

Subject

Mitochondrion

Coenzyme Q – cytochrome c reductase

Cytochrome c oxidase

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