Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

B. Zorov, Dmitry; Juhaszova, Magdalena; J. Sollott, Steven

doi:10.1152/physrev.00026.2013

Public

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

Published in Physiological Reviews • Jul 1, 2014

Authors:

Dmitry B. Zorov

Magdalena Juhaszova

Steven J. Sollott

Abstract

Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of potentially damaging levels of reactive oxygen species (ROS), Ca(2+), etc., which must be normalized. Evidence suggests that brief mitochondrial permeability transition pore (mPTP) openings play an important physiol...

Subject

Mitochondrion

Mitochondrial ROS

Reactive oxygen species

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