Phase I trial on the safety of topical rhVEGF on chronic neuropathic diabetic foot ulcers

Hanft, J.R.; Pollak, R.A.; Barbul, A.; Gils, C.van; Kwon, P.S.; Gray, S.M.; Lynch, C.J.; Semba, C.P.; Breen, T.J.

doi:10.12968/jowc.2008.17.1.27917

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Phase I trial on the safety of topical rhVEGF on chronic neuropathic diabetic foot ulcers

Shared by NobleBlocks on Jan 1, 2008 • 12:00 AM UTC

Authors:

J.R. Hanft

R.A. Pollak

A. Barbul

Abstract

Objective: To assess the safety/tolerability and perform a preliminary efficacy evaluation of a multiple-dosing regimen of recombinant human vascular endothelial growth factor (VEGF 165 or rhVEGF; telbermin) applied topically to chronic diabetic neuropathic foot ulcers. Method: Subjects with type 1 ...

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