Evaluation of 10 genes encoding cardiac proteins in Doberman Pinschers with dilated cardiomyopathy.

Lynne O'Sullivan, M; R O'Grady, Michael; Glen Pyle, W; F Dawson, John

doi:10.2460/ajvr.72.7.932

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Evaluation of 10 genes encoding cardiac proteins in Doberman Pinschers with dilated cardiomyopathy.

Shared by NobleBlocks on Jul 1, 2011 • 12:00 AM UTC

Authors:

M Lynne O'Sullivan

Michael R O'Grady

W Glen Pyle

Abstract

OBJECTIVE: To identify a causative mutation for dilated cardiomyopathy (DCM) in Doberman Pinschers by sequencing the coding regions of 10 cardiac genes known to be associated with familial DCM in humans. ANIMALS: 5 Doberman Pinschers with DCM and congestive heart failure and 5 control mixed-breed do...

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