The Variant rs1867277 in FOXE1 Gene Confers Thyroid Cancer Susceptibility through the Recruitment of USF1/USF2 Transcription Factors

Landa, Iñigo; Ruiz‐Llorente, Sergio; Montero‐Conde, Cristina; Inglada‐Pérez, Lucía; Schiavi, Francesca; Leskelä, Susanna; Pita, Guillermo; L. Milne, Roger; Maravall, Javier; Ramos, Ignacio; Andía, Victor; Rodríguez-Poyo, Paloma; Jara-Albarrán, Antonino; Meoro, Amparo; Del Peso, Cristina; Arribas, Luis; Iglesias, Pedro; Caballero‐Villarraso, Javier; Serrano, Joaquín; Picó, Antonio; Pomares, Francisco; Giménez, Gabriel; López-Mondéjar, Pedro; Castello, Roberto; Merante Boschin, Isabella; Pelizzo, Maria-Rosa; Mauricio, Dı́dac; Opocher, Giuseppe; Rodríguez‐Antona, Cristina; González‐Neira, Anna; Matías‐Guiu, Xavier; Santisteban, Pilar; Robledo, Mercedes

doi:10.1371/journal.pgen.1000637

Public

The Variant rs1867277 in FOXE1 Gene Confers Thyroid Cancer Susceptibility through the Recruitment of USF1/USF2 Transcription Factors

Published in PLoS Genetics • Sep 3, 2009

Authors:

Iñigo Landa

Sergio Ruiz‐Llorente

Cristina Montero‐Conde

Abstract

In order to identify genetic factors related to thyroid cancer susceptibility, we adopted a candidate gene approach. We studied tag- and putative functional SNPs in genes involved in thyroid cell differentiation and proliferation, and in genes found to be differentially expressed in thyroid carcinom...

Subject

Biology

Single-nucleotide polymorphism

Thyroid cancer

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