Familial antiphospholipid antibody syndrome: Criteria for disease and evidence for autosomal dominant inheritance

Goel, Niti; L. Ortel, Thomas; Bali, Deeksha; P. Anderson, Joshua; Gourley, Ian; R. Smith, Howard; A. Morris, Colleen; DeSimone, Muriel; Ware Branch, D.; M Ford, P; H. Berdeaux, Donald; Roubey, Robert; D. Kostyu, Donna; F. Kingsmore, Stephen; Thiel, T.J.; I. Amos, Christopher; F. Seldin, Michael

doi:10.1002/1529-0131(199902)42:2<318::aid-anr15>3.0.co;2-5

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Familial antiphospholipid antibody syndrome: Criteria for disease and evidence for autosomal dominant inheritance

Published in Arthritis & Rheumatism • Feb 1, 1999

Authors:

Niti Goel

Thomas L. Ortel

Deeksha Bali

Abstract

OBJECTIVE: To develop diagnostic criteria for a familial form of antiphospholipid antibody syndrome (APS), identify families with >1 affected member, examine possible modes of inheritance, and determine linkage to potential candidate genes. METHODS: Family members of probands with primary APS were a...

Subject

Proband

Candidate gene

Genetic linkage

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