Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.

The present study investigates the hypothesis that endothelium-dependent relaxation of vascular smooth muscle may be mediated through the formation of cGMP. Relaxation of the rat thoracic aorta to acetylcholine, histamine, and Ca++ ionophore A23187 was associated with increased levels of cGMP in a t... View More