Hydrogenases: Hydrogen-Activating Enzymes

Hydrogen is an important metabolite for many microrganisms. H2 is either produced or consumed by hydrogenase enzymes, according to the reaction: H2⇌2 H+ + 2 e−. The catalytic sites of the two major families of hydrogenases include a dinuclear center, either NiFe (see picture) or FeFe, along with pro... View More