A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis

Gando, Satoshi; Saitoh, Daizoh; Ishikura, Hiroyasu; Ueyama, Masashi; Otomo, Yasuhiro; Oda, Shigeto; Kushimoto, Shigeki; Tanjoh, Katsuhisa; Mayumi, Toshihiko; Ikeda, Toshiaki; Iba, Toshiaki; Eguchi, Yutaka; Okamoto, Kohji; Ogura, Hiroshi; Koseki, Kazuhide; Sakamoto, Yuichiro; Takayama, Yasuhiro; Shirai, Kunihiro; Takasu, Osamu; Inoue, Yoshiaki; Mashiko, Kunihiro; Tsubota, Takaya; Endo, Shigeatsu

doi:10.1186/cc13163

Public

A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis

Published in Critical Care • Dec 16, 2013

Authors:

Satoshi Gando

Daizoh Saitoh

Hiroyasu Ishikura

Abstract

INTRODUCTION: To test the hypothesis that the administration of antithrombin concentrate improves disseminated intravascular coagulation (DIC), resulting in recovery from DIC and better outcomes in patients with sepsis, we conducted a prospective, randomized controlled multicenter trial at 13 critic...

Subject

Medicine

Disseminated intravascular coagulation

Antithrombin

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