Effects of Intravenous Zoledronic Acid Once Yearly on Bone Remodeling and Bone Structure

R. Recker, Robert; D. Delmas, Pierre; Halse, Johan; R. Reid, Ian; Boonen, Steven; Alberto García-Hernández, Pedro; Supronik, Jerzy; Michael Lewiecki, E.; Alberto Ochoa, Luis; D. Miller, Paul; Hu, Huilin; Mesenbrink, Peter; Hartl, Florian; A. Gasser, Jürg; Fink Eriksen, Erik

doi:10.1359/jbmr.070906

Public

Effects of Intravenous Zoledronic Acid Once Yearly on Bone Remodeling and Bone Structure

Published in Journal of Bone and Mineral Research • Sep 24, 2007

Authors:

Robert R. Recker

Pierre D. Delmas

Johan Halse

Abstract

UNLABELLED: In a substudy of the HORIZON pivotal fracture trial, in which yearly intravenous zoledronic acid 5 mg was found to significantly reduce risk of various fracture types in patients with postmenopausal osteoporosis, 152 patients underwent bone biopsy. Zoledronic acid reduced bone turnover b...

Subject

Zoledronic acid

Medicine

Bone remodeling

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