Effects of intravenous zoledronic acid once yearly on bone remodeling and bone structure.

RR, Recker; PD, Delmas; J, Halse; IR, Reid; S, Boonen; PA, García-Hernandez; J, Supronik; EM, Lewiecki; L, Ochoa; P, Miller; H, Hu; P, Mesenbrink; F, Hartl; J, Gasser; EF, Eriksen

doi:10.1359/jbmr.070906

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Effects of intravenous zoledronic acid once yearly on bone remodeling and bone structure.

Shared by NobleBlocks on Jan 1, 2008 • 12:00 AM UTC

Authors:

Recker RR

Delmas PD

Halse J

Abstract

Unlabelled In a substudy of the HORIZON pivotal fracture trial, in which yearly intravenous zoledronic acid 5 mg was found to significantly reduce risk of various fracture types in patients with postmenopausal osteoporosis, 152 patients underwent bone biopsy. Zoledronic acid reduced bone turnover by...

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