Fibroblast Growth Factor-12 (FGF12) Translocation into Intestinal Epithelial Cells Is Dependent on a Novel Cell-penetrating Peptide Domain

Nakayama, Fumiaki; Yasuda, Takeshi; Umeda, Sachiko; Asada, Masahiro; Imamura, Toru; Meineke, Viktor; Akashi, Makoto

doi:10.1074/jbc.m110.198267

Public

Fibroblast Growth Factor-12 (FGF12) Translocation into Intestinal Epithelial Cells Is Dependent on a Novel Cell-penetrating Peptide Domain

Published in Journal of Biological Chemistry • Apr 26, 2011

Authors:

Fumiaki Nakayama

Takeshi Yasuda

Sachiko Umeda

Abstract

The extracellular effect of fibroblast growth factor-12 (FGF12) remains unknown because FGF12 cannot activate any fibroblast growth factor receptors (FGFRs), and FGF12 is not currently thought to be released from cells. We reported previously that FGF12 plays an intracellular role in the inhibition ...

Subject

Chromosomal translocation

Cell biology

Peptide

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