Propylthiouracil (PTU)-Induced Agranulocytosis Treated with Recombinant Human Granulocyte Colony-Stimulating Factor (G-CSF)

Balkin, Michael; Buchholtz, Michael; Ortíz, José; Green, Andrew

doi:10.1089/thy.1993.3.305

Public

Propylthiouracil (PTU)-Induced Agranulocytosis Treated with Recombinant Human Granulocyte Colony-Stimulating Factor (G-CSF)

Published in Thyroid • Jan 1, 1993

Authors:

Michael Balkin

Michael Buchholtz

José Ortíz

Abstract

Two premenopausal female patients with Graves' hyperthyroidism and propylthiouracil (PTU)-induced agranulocytosis are presented. The first patient, age 47, received 300 mg of PTU per day and developed agranulocytosis within 6 weeks of the commencement of therapy. There were no granulocytes in the pe...

Subject

Medicine

Propylthiouracil

Granulocyte colony-stimulating factor

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