Rates of bone loss in the appendicular and axial skeletons of women. Evidence of substantial vertebral bone loss before menopause.

Lawrence Riggs, B.; W. Wahner, Heinz; Joseph Melton, L.; S. Richelson, L.; L. Judd, Howard; P. Offord, Kenneth

doi:10.1172/jci112462

Public

Rates of bone loss in the appendicular and axial skeletons of women. Evidence of substantial vertebral bone loss before menopause.

Published in Journal of Clinical Investigation • May 1, 1986

Authors:

B. Lawrence Riggs

Heinz W. Wahner

L. Joseph Melton

Abstract

We made longitudinal measurements of bone mineral density (BMD) in 139 normal women (ages 20-88 yr) at midradius (99% cortical bone) and lumbar spine (approximately 70% trabecular bone) by single- and dual-photon absorptiometry. BMD was measured 2-6 (median, 3) times over an interval of 0.8-3.4 yr (...

Subject

Menopause

Medicine

Osteoporosis

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