Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases

Zhang, Wenjun; J. Bieker, James

doi:10.1073/pnas.95.17.9855

Public

Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases

Published in Proceedings of the National Academy of Sciences • Aug 18, 1998

Authors:

Wenjun Zhang

James J. Bieker

Abstract

Erythroid Krüppel-like factor (EKLF) is a red cell-specific transcriptional activator that is crucial for consolidating the switch to high levels of adult beta-globin expression during erythroid ontogeny. EKLF is required for integrity of the chromatin structure at the beta-like globin locus, and it...

Subject

Chromatin

Transcription factor

Histone

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