Potential contribution of tumor suppressor p53 in the host defense against hepatitis C virus†

Dharel, Narayan; Kato, Naoya; Muroyama, Ryosuke; Taniguchi, Hiroyoshi; Otsuka, Motoyuki; Wang, Yue; Jazag, Amarsanaa; Shao, Run–Xuan; Chang, Jin‐Hai; K. Adler, Mark; Kawabe, Takao; Omata, Masao

doi:10.1002/hep.22176

Public

Potential contribution of tumor suppressor p53 in the host defense against hepatitis C virus†

Published in Hepatology • Jan 25, 2008

Authors:

Narayan Dharel

Naoya Kato

Ryosuke Muroyama

Abstract

UNLABELLED: Infection by hepatitis C virus (HCV) usually results into chronic hepatitis that can ultimately lead to cirrhosis and hepatocellular carcinoma. Type 1 interferons (IFN-alpha/beta) constitute the primary cellular defense against viral infection including HCV. IFN binding to their receptor...

Subject

Interferon

Biology

STAT2

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