Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine compared to a 23-valent pneumococcal polysaccharide vaccine in pneumococcal vaccine-naive adults

A. Jackson, Lisa; Gurtman, Alejandra; van Cleeff, Martin; U. Jansen, Kathrin; Jayawardene, Deepthi; Devlin, Carmel; A. Scott, Daniel; A. Emini, Emilio; C. Gruber, William; Schmöele-Thoma, Beate

doi:10.1016/j.vaccine.2013.04.085

Public

Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine compared to a 23-valent pneumococcal polysaccharide vaccine in pneumococcal vaccine-naive adults

Published in Vaccine • May 18, 2013

Authors:

Lisa A. Jackson

Alejandra Gurtman

Martin van Cleeff

Abstract

BACKGROUND: Streptococcus pneumoniae is a major cause of morbidity and mortality among adults 50 years of age and older in the United States. Pneumococcal conjugate vaccines are efficacious against pneumococcal disease in children and may also offer advantages in adults. METHODS: We performed a rand...

Subject

Pneumococcal conjugate vaccine

Medicine

Pneumococcal polysaccharide vaccine

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