Serum Glial Fibrillary Acidic Protein Is a Highly Specific Biomarker for Traumatic Brain Injury in Humans Compared With S-100B and Neuron-Specific Enolase

Honda, Masahiro; Tsuruta, Ryosuke; Kaneko, Tadashi; Kasaoka, Shunji; Yagi, Takeshi; Todani, Masaki; Fujita, Motoki; Izumi, Tomonori; Maekawa, Tsuyoshi

doi:10.1097/ta.0b013e3181bbd485

Public

Serum Glial Fibrillary Acidic Protein Is a Highly Specific Biomarker for Traumatic Brain Injury in Humans Compared With S-100B and Neuron-Specific Enolase

Published in The Journal of Trauma: Injury, Infection, and Critical Care • Mar 25, 2010

Authors:

Masahiro Honda

Ryosuke Tsuruta

Tadashi Kaneko

Abstract

BACKGROUND: Serum glial fibrillary acidic protein (GFAP) is a specific predictor of brain damage and neurologic outcome in patients with traumatic brain injury (TBI). In this study, serum GFAP, S-100B, and neuron-specific enolase (NSE) were compared in the same samples from severe trauma patients to...

Subject

Glial fibrillary acidic protein

Enolase

Traumatic brain injury

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