Reduced Urinary Excretion of Nitric Oxide Metabolites and Increased Plasma Levels of Asymmetric Dimethylarginine in Men with Essential Hypertension

Surdacki, Andrzej; Nowicki, Michał; Sandmann, Joerg; Tsikas, Dimitrios; Boeger, Rainer; M. Bode-Boeger, Stephanie; Kruszelnicka-Kwiatkowska, O.; Kokot, F; S. Dubiel, Jacek; C. Froelich, Juergen

doi:10.1097/00005344-199904000-00020

Public

Reduced Urinary Excretion of Nitric Oxide Metabolites and Increased Plasma Levels of Asymmetric Dimethylarginine in Men with Essential Hypertension

Published in Journal of Cardiovascular Pharmacology • Apr 1, 1999

Authors:

Andrzej Surdacki

Michał Nowicki

Joerg Sandmann

Abstract

Our aim was to investigate systemic nitric oxide (NO) production and its potential determinants such as insulin resistance, dyslipidemia, and circulating methylated analogs of L-arginine in uncomplicated essential hypertension (EH). Nineteen newly diagnosed, untreated male subjects with mild pure un...

Subject

Asymmetric dimethylarginine

Nitric oxide

Essential hypertension

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