Human Wharton’s jelly-derived mesenchymal stromal cells reduce renal fibrosis through induction of native and foreign hepatocyte growth factor synthesis in injured tubular epithelial cells

Du, Tao; Zou, Xiangyu; Cheng, Jun; Wu, Shuai; Zhong, Liang; Ju, Guanqun; Zhu, Jiang; Liu, Guohua; Zhu, Yingjian; Xia, Shujie

doi:10.1186/scrt215

Public

Human Wharton’s jelly-derived mesenchymal stromal cells reduce renal fibrosis through induction of native and foreign hepatocyte growth factor synthesis in injured tubular epithelial cells

Published in Stem Cell Research & Therapy • Jun 4, 2013

Authors:

Tao Du

Xiangyu Zou

Jun Cheng

Abstract

INTRODUCTION: Based on some well-documented reports, we attempted to clarify the antifibrotic mechanisms of human Wharton's-jelly-derived mesenchymal stromal cells (WJ-MSCs) from the perspective of induction of hepatocyte growth factor (HGF) expression in tubular epithelial cells (TECs). METHODS: A ...

Subject

Hepatocyte growth factor

Mesenchymal stem cell

Immunostaining

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!