Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury

Busto, Raul; Dalton Dietrich, W.; Y.‐T. Globus, Mordecai; Valdés, Isabel; Scheinberg, Peritz; D. Ginsberg, Myron

doi:10.1038/jcbfm.1987.127

Public

Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury

Published in Journal of Cerebral Blood Flow & Metabolism • Dec 1, 1987

Authors:

Raul Busto

W. Dalton Dietrich

Mordecai Y.‐T. Globus

Abstract

We have tested whether small intraischemic variations in brain temperature influence the outcome of transient ischemia. To measure brain temperature, a thermocouple probe was placed stereotaxically into the left dorsolateral striatum of rats prior to 20 min of four-vessel occlusion. Rectal temperatu...

Subject

Ischemia

Phosphocreatine

Striatum

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