Phenotypic and genotypic analysis of clinical HIV-1 isolates reveals extensive protease inhibitor cross-resistance: a survey of over 6000 samples

Hertogs, Kurt; Bloor, Stuart; D. Kemp, Sharon; Van den Eynde, Christel; M. Alcorn, Timothy; Pauwels, Rudi; Van Houtte, Margriet; Staszewski, Schlomo; Miller, Veronica; Larder, Brendan

doi:10.1097/00002030-200006160-00018

Public

Phenotypic and genotypic analysis of clinical HIV-1 isolates reveals extensive protease inhibitor cross-resistance: a survey of over 6000 samples

Published in AIDS • Jun 1, 2000

Authors:

Kurt Hertogs

Stuart Bloor

Sharon D. Kemp

Abstract

OBJECTIVE: To evaluate in HIV-1 the extent of phenotypic and genotypic antiretroviral drug resistance and cross-resistance towards the protease inhibitors (PIs) saquinavir, ritonavir, indinavir and nelfinavir among a set of patient samples originating from European and US routine clinical practice a...

Subject

Nelfinavir

Saquinavir

Indinavir

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