Insulin‐Directed Synthesis of Fluorescent Gold Nanoclusters: Preservation of Insulin Bioactivity and Versatility in Cell Imaging

Liu, Chien‐Liang; Wu, Hung‐Tsung; Hsiao, Yi‐Hsuan; Lai, Chih‐Wei; Shih, Chun‐Wei; Peng, Yung‐Kang; Tang, Kuo‐Chun; Chang, Hsing‐Wei; Chien, Yun‐Chen; Hsiao, Jong‐Kai; Cheng, Juei‐Tang; Chou, Pi‐Tai

doi:10.1002/anie.201100299

Public

Insulin‐Directed Synthesis of Fluorescent Gold Nanoclusters: Preservation of Insulin Bioactivity and Versatility in Cell Imaging

Published in Angewandte Chemie International Edition • Jun 17, 2011

Authors:

Chien‐Liang Liu

Hung‐Tsung Wu

Yi‐Hsuan Hsiao

Abstract

Go for gold: As-prepared insulin–Au nanoclusters (NCs) show intense red fluorescence, excellent biocompatibility, and preservation of natural insulin bioactivity in lowering the blood-glucose level. Their versatility in applications is demonstrated by fluorescence imaging, X-ray computed tomography,...

Subject

Nanoclusters

Insulin

Fluorescence

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