Intermittent versus Continuous Androgen Deprivation in Prostate Cancer

Hussain, Maha; M. Tangen, Catherine; L. Berry, Donna; S. Higano, Celestia; David Crawford, E.; Liu, Glenn; Wilding, George; M. Prescott, Stephen; Sundaram, S.K.; J. Small, Eric; A. Dawson, Nancy; Donnelly, Bryan; Venner, Peter; N. Vaishampayan, Ulka; F. Schellhammer, Paul; I. Quinn, David; Raghavan, Derek; Ely, Benjamin; M. Moinpour, Carol; J. Vogelzang, Nicholas; M. Thompson, Ian

doi:10.1056/nejmoa1212299

Public

Intermittent versus Continuous Androgen Deprivation in Prostate Cancer

Published in New England Journal of Medicine • Apr 3, 2013

Authors:

Maha Hussain

Catherine M. Tangen

Donna L. Berry

Abstract

BACKGROUND: Castration resistance occurs in most patients with metastatic hormone-sensitive prostate cancer who are receiving androgen-deprivation therapy. Replacing androgens before progression of the disease is hypothesized to prolong androgen dependence. METHODS: Men with newly diagnosed, metasta...

Subject

Medicine

Prostate cancer

Androgen deprivation therapy

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