NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens

L. Keyburn, Anthony; D. Boyce, John; K. Vaz, Paola; L. Bannam, Trudi; Ford, Mark; Parker, Dane; Di Rubbo, Antonio; I. Rood, Julian; J. Moore, Robert

doi:10.1371/journal.ppat.0040026

Public

NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens

Published in PLoS Pathogens • Feb 5, 2008

Authors:

Anthony L. Keyburn

John D. Boyce

Paola K. Vaz

Abstract

For over 30 years a phospholipase C enzyme called alpha-toxin was thought to be the key virulence factor in necrotic enteritis caused by Clostridium perfringens. However, using a gene knockout mutant we have recently shown that alpha-toxin is not essential for pathogenesis. We have now discovered a ...

Subject

Clostridium perfringens

Virulence

Biology

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