Clustering of α 5 β 1 integrins determines adhesion strength whereas α v β 3 and talin enable mechanotransduction

A key molecular link between cells and the extracellular matrix is the binding between fibronectin and integrins α 5 β 1 and α v β 3 . However, the roles of these different integrins in establishing adhesion remain unclear. We tested the adhesion strength of fibronectin-integrin-cytoskeleton linkage... View More