Glucagonostatic Actions and Reduction of Fasting Hyperglycemia by Exogenous Glucagon-Like Peptide I(7–36) amide in type I diabetic patients

Creutzfeldt, W.; Kleine, N.; Willms, B.; Ørskov, Cathrine; J. Holst, Jens; A. Nauck, Michael

doi:10.2337/diacare.19.6.580

Public

Glucagonostatic Actions and Reduction of Fasting Hyperglycemia by Exogenous Glucagon-Like Peptide I(7–36) amide in type I diabetic patients

Published in Diabetes Care • Jun 1, 1996

Authors:

W. Creutzfeldt

N. Kleine

B. Willms

Abstract

OBJECTIVE: Glucagon-like peptide I(7-36) amide (GLP-1) is a physiological incretin hormone that, in slightly supraphysiological doses, stimulates insulin secretion, lowers glucagon concentrations, and thereby normalizes elevated fasting plasma glucose concentrations in type II diabetic patients. It ...

Subject

Internal medicine

Endocrinology

Insulin

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