A randomized prospective study of lumpectomy margin assessment with use of MarginProbe in patients with nonpalpable breast malignancies.

Schnabel, Freya; K Boolbol, Susan; Gittleman, Mark; Karni, Tami; Tafra, Lorraine; Feldman, Sheldon; Police, Alice; B Friedman, Neil; Karlan, Scott; Holmes, Dennis; C Willey, Shawna; Carmon, Moshe; Fernandez, Kristen; Akbari, Stephanie; Harness, Jay; Guerra, Lisa; Frazier, Thomas; Lane, Karen; M Simmons, Rache; Estabrook, Alison; Allweis, Tanir

doi:10.1245/s10434-014-3602-0

Public

A randomized prospective study of lumpectomy margin assessment with use of MarginProbe in patients with nonpalpable breast malignancies.

Shared by NobleBlocks on May 1, 2014 • 12:00 AM UTC

Authors:

Freya Schnabel

Susan K Boolbol

Mark Gittleman

Abstract

BACKGROUND: The presence of tumor cells at the margins of breast lumpectomy specimens is associated with an increased risk of ipsilateral tumor recurrence. Twenty to 30 % of patients undergoing breast-conserving surgery require second procedures to achieve negative margins. This study evaluated the ...

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