Angiogenic Effects of Human Multipotent Stromal Cell Conditioned Medium Activate the PI3K-Akt Pathway in Hypoxic Endothelial Cells to Inhibit Apoptosis, Increase Survival, and Stimulate Angiogenesis

Hung, Shih‐Chieh; Pochampally, Radhika; Chen, Sy-Chi; Hsu, Shu‐Ching; J. Prockop, Darwin

doi:10.1634/stemcells.2006-0686

Public

Angiogenic Effects of Human Multipotent Stromal Cell Conditioned Medium Activate the PI3K-Akt Pathway in Hypoxic Endothelial Cells to Inhibit Apoptosis, Increase Survival, and Stimulate Angiogenesis

Published in Stem Cells • Jun 1, 2007

Authors:

Shih‐Chieh Hung

Radhika Pochampally

Sy-Chi Chen

Abstract

Recent reports indicated that vascular remodeling and angiogenesis are promoted by conditioned medium from the cells referred to as multipotent stromal cells (MSCs). However, the molecular events triggered by MSC-conditioned medium (CdM) were not defined. We examined the effects of CdM from human MS...

Subject

Angiogenesis

Biology

Stromal cell

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!