Flexible Porous Metal-Organic Frameworks for a Controlled Drug Delivery

Horcajada, Patricia; Serre, Christian; Maurin, Guillaume; A. Ramsahye, Naseem; Balas, Francisco; Vallet‐Regí, María; Sebban, Muriel; Taulelle, Francis; Férey, Gérard

doi:10.1021/ja710973k

Public

Flexible Porous Metal-Organic Frameworks for a Controlled Drug Delivery

Published in Journal of the American Chemical Society • May 1, 2008

Authors:

Patricia Horcajada

Christian Serre

Guillaume Maurin

Abstract

Flexible nanoporous chromium or iron terephtalates (BDC) MIL-53(Cr, Fe) or M(OH)[BDC] have been used as matrices for the adsorption and in vitro drug delivery of Ibuprofen (or alpha- p-isobutylphenylpropionic acid). Both MIL-53(Cr) and MIL-53(Fe) solids adsorb around 20 wt % of Ibuprofen (Ibuprofen/...

Subject

Ibuprofen

Chemistry

Nanoporous

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