Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies

M. Blows, Fiona; Driver, Kristy; K. Schmidt, Marjanka; Broeks, Annegien; E. van Leeuwen, Flora; Wesseling, Jelle; C.U. Cheang, Maggie; A. Gelmon, Karen; O. Nielsen, Torsten; Blomqvist, Carl; Heikkilä, Päivi; Heikkinen, Tuomas; Nevanlinna, Heli; A. Akslen, Lars; R. Bégin, Louis; D. Foulkes, William; J. Couch, Fergus; Wang, Xianshu; Cafourek, Vicky; E. Olson, Janet; Baglietto, Laura; G. Giles, Graham; Severi, Gianluca; McLean, Catriona; C. Southey, Melissa; A. Rakha, Emad; R. Green, Andrew; O. Ellis, Ian; E. Sherman, Mark; Lissowska, Jolanta; F. Anderson, William; Cox, Angela; S. Cross, Simon; Reed, Malcolm; Provenzano, Elena; Dawson, Sarah‐Jane; M. Dunning, Alison; K. Humphreys, Manjeet; F. Easton, Douglas; García‐Closas, Montserrat; Caldas, Carlos; D.P. Pharoah, Paul; G. Huntsman, David

doi:10.1371/journal.pmed.1000279

Public

Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies

Published in PLoS Medicine • May 25, 2010

Authors:

Fiona M. Blows

Kristy Driver

Marjanka K. Schmidt

Abstract

BACKGROUND: Immunohistochemical markers are often used to classify breast cancer into subtypes that are biologically distinct and behave differently. The aim of this study was to estimate mortality for patients with the major subtypes of breast cancer as classified using five immunohistochemical mar...

Subject

Breast cancer

Immunohistochemistry

Subtyping

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