Novel mucus-penetrating liposomes as a potential oral drug delivery system: preparation, in vitro characterization, and enhanced cellular uptake

Gan, Yong; Li, Xiuying; Chen, Dan; Le, Chaoyi; Zhu, Chunliu; Hovgaard, Lars; Yang, Mingshi

doi:10.2147/ijn.s25741

Public

Novel mucus-penetrating liposomes as a potential oral drug delivery system: preparation, in vitro characterization, and enhanced cellular uptake

Published in International Journal of Nanomedicine • Dec 1, 2011

Authors:

Yong Gan

Xiuying Li

Dan Chen

Abstract

BACKGROUND: The aim of this study was to investigate the intestinal mucus-penetrating properties and intestinal cellular uptake of two types of liposomes modified by Pluronic F127 (PF127). METHODS: The two types of liposomes, ie, PF127-inlaid liposomes and PF127-adsorbed liposomes, were prepared by ...

Subject

Liposome

Drug delivery

In vitro

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