In vivo detection of GABA and glutamate with MEGA‐PRESS: Reproducibility and gender effects

L. O'Gorman, Ruth; Michels, Lars; A.E. Edden, Richard; B. Murdoch, James; Martin, Ernst

doi:10.1002/jmri.22520

Public

In vivo detection of GABA and glutamate with MEGA‐PRESS: Reproducibility and gender effects

Published in Journal of Magnetic Resonance Imaging • Apr 20, 2011

Authors:

Ruth L. O'Gorman

Lars Michels

Richard A.E. Edden

Abstract

PURPOSE: To evaluate the reproducibility of γ-amino-butyric acid (GABA) and glutamate concentrations derived using three different spectral fitting methods, and to investigate gender-related differences in neurotransmitter levels. MATERIALS AND METHODS: Single voxel MEGA-edited PRESS MR spectra were...

Subject

Reproducibility

Glutamate receptor

Glutamine

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