Microvesicles Derived from Human Wharton's Jelly Mesenchymal Stem Cells Promote Human Renal Cancer Cell Growth and Aggressiveness through Induction of Hepatocyte Growth Factor

Du, Tao; Ju, Guanqun; Wu, Shuai; Cheng, Zhongliang; Cheng, Jun; Zou, Xiangyu; Zhang, Guangyuan; Miao, Shuai; Liu, Guohua; Zhu, Yingjian

doi:10.1371/journal.pone.0096836

Public

Microvesicles Derived from Human Wharton's Jelly Mesenchymal Stem Cells Promote Human Renal Cancer Cell Growth and Aggressiveness through Induction of Hepatocyte Growth Factor

Published in PLoS ONE • May 5, 2014

Authors:

Tao Du

Guanqun Ju

Shuai Wu

Abstract

In our previous study, microvesicles (MVs) released from human Wharton's jelly mesenchymal stem cells (hWJ-MSCs) retard the growth of bladder cancer cells. We would like to know if MVs have a similar effect on human renal cell carcinoma (RCC). By use of cell culture and the BALB/c nu/nu mice xeno-gr...

Subject

Wharton's jelly

Hepatocyte growth factor

Protein kinase B

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